Is benfotiamine safe to take?

When taken by mouth: Benfotiamine is likely safe at doses of up to 600 mg daily for up to 24 weeks. Side effects are rare, but some people have reported stomach problems and skin rashes.

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What are the side effects of taking benfotiamine?

Possible Side Effects
  • Upset stomach.
  • Nausea.
  • Dizziness.
  • Hair loss.
  • Weight gain.
  • Body odor.
  • Decrease in blood pressure.

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Can benfotiamine cause nerve damage?

Our findings suggest that high-dose benfotiamine (300 mg/day) supplementation over 24 months has no significant effects upon peripheral nerve function or soluble markers of inflammation in patients with type 1 diabetes.

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What are the benefits of taking benfotiamine?

Benfotiamine inhibits the synthesis of AGEs and thus decrease the metabolic stress. Benfotiamine thus helps in vascular complications associated with diabetes.

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Can healthy people take benfotiamine?

Benfotiamine is generally considered safe for most people when taken at standard doses, though long-term safety has not been studied. In clinical trials, side effects were mild and included gastrointestinal issues and skin reactions [7].

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Vitamin B therapy dangerous for diabetics with kidney disease

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Who needs benfotiamine?

One small study suggests that a high daily dose of benfotiamine may help curb drinking in women with alcohol use disorder. Another study found it may ease mental distress in men who've stopped drinking to recover from severe alcoholism. Still, much more research is needed.

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Can vitamin B1 be harmful?

Toxicity. It is unlikely to reach a toxic level of thiamin from food sources alone. In the setting of very high intakes, the body will absorb less of the nutrient and flush out any excess amount through the urine. There is no established toxic level of thiamin.

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How long should you take benfotiamine?

Therapeutic benefits can be seen as early as 3 weeks, with the most significant improvements occurring in patients taking the highest-dose of benfotiamine, that is, 600 mg/day at 6 weeks.

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Can vitamin B1 cause high blood pressure?

When the amount of vitamin B1, also known as thiamine exceeds the normal levels in the body, it can cause hypertension or high blood pressure.

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Is benfotiamine the same as Sulbutiamine?

Like disulfide derivatives, benfotiamine may be useful for the treatment of acute peripheral syndromes of thiamine deficiency because it is better absorbed than thiamine, but in contrast to sulbutiamine, it seems to be devoid of specific effects on brain function.

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Does benfotiamine cure neuropathy?

Treatment was well tolerated by patients, and no benfotiamine-drug interactions were reported. A study of 20 patients given 400mg daily of benfotiamine showed improvement in neuropathy scores and decrease in pain complaints over a 3-week period.

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Is benfotiamine good for kidneys?

Taken together, these data suggest that benfotiamine protects the peritoneal membrane and remnant kidney in a rat model of peritoneal dialysis and uremia. Peritoneal dialysis (PD) is a well accepted alternative to hemodialysis in the treatment of end-stage renal disease.

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Does benfotiamine raise blood sugar?

Benfotiamine treatment had no significant effect on blood glucose levels.

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Is benfotiamine anti inflammatory?

Benfotiamine is a synthetic vitamin B1 (thiamine) derivate exerting potentially anti-inflammatory effects.

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What are the symptoms of low vitamin B1?

Symptoms of thiamine (B1) deficiency
  1. Loss of appetite. Experiencing an atypical loss of appetite can be one of the earliest symptoms of thiamine deficiency. ...
  2. Fatigue. ...
  3. Irritability. ...
  4. Nerve damage. ...
  5. Tingling arms and legs. ...
  6. Blurry vision. ...
  7. Nausea and vomiting. ...
  8. Delirium.

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Is thiamine B1 healthy?

A dose of vitamins B1 and B12 can help improve nerve pain in people with diabetes and may reduce the need for painkillers. Improves memory. Getting enough thiamine can help improve concentration and memory. Because of its positive effect on attitude and brain function, it is also known as a "morale vitamin".

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Can I take vitamin B1 everyday?

The recommended daily amount of thiamin for adult men is 1.2 milligrams and for adult women is 1.1 milligrams.

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Can you take too much vitamin B1?

Thiamine is generally safe. Very high doses may cause stomach upset. Taking any one of the B vitamins for a long period of time can result in an imbalance of other important B vitamins. For this reason, you may want to take a B-complex vitamin, which includes all the B vitamins.

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Should benfotiamine be taken with or without food?

It is an amino acid, and it should be taken on an empty stomach, definitely not with protein. Take it an hour before a meal or 2 hours afterwards. The recommended dosage is 2-5 gm/daily. I purchased this bulk powder by BulkSupplements .

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What is the difference between B1 and B12?

Vitamin B1 is thiamine whereas vitamin B12 is cobalamin. Vitamin B1 plays a crucial role in nerve, muscle and heart function whereas vitamin B12 helps in the functioning of the central nervous system.

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What is the best form of vitamin B1?

Wheat germ, whole wheat, peas, beans, enriched flour, fish, peanuts, and meat are all good sources of vitamin B1.

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How much B1 should you take a day?

How much vitamin B1 do we need? In the U.S., the recommended daily allowance (RDA) of thiamin taken by mouth is 1.2 mg for males and 1.1 mg for females over the age of 18 years. Pregnant or breastfeeding women of any age should consume 1.4 mg each day.

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Can you take benfotiamine and metformin together?

Your doctor may advise BENFOTIAMINE+METFORMIN with or without other medications to control your blood sugar levels. However, it is advised to maintain a proper diet and exercise to achieve the controlled blood sugar levels while using BENFOTIAMINE+METFORMIN with or without other antidiabetic drugs.

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Is benfotiamine the same as vitamin B1?

Benfotiamine is similar to thiamine (vitamin B1), but is absorbed by the body better than thiamine. The body changes benfotiamine to thiamine. Since the body absorbs benfotiamine better than thiamine, benfotiamine can increase how much thiamine is in the body.

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Is 100mg of B1 too much?

Mild thiamine deficiency – the usual dose for adults is between 25mg and 100mg, taken once a day. Severe thiamine deficiency – the usual dose for adults is 100mg, taken 2 or 3 times a day. If your child is prescribed thiamine, the doctor will use your child's weight to work out the right dose.

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